Renal hypoperfusion occurs as a result of reduced cardiac output, resulting in the activation of the renin–angiotensin–aldosterone system, which compensates for the hypoperfusion. However ...

chronic kidney disease (CKD), the metabolic syndrome, and diabetes mellitus (Schrier, R. W. et al. Clin. J. Am. Soc. Nephrol. in press). The finding that angiotensin II and aldosterone are ...

With aldosterone synthase inhibitors, you worry about potassium levels and hyperkalemia. That has been a limitation of these types of therapies, especially for patients with any degree of renal ...

Advances in hypertension as reported at ACC 2025 include two new therapies that achieve significant blood pressure (BP) reduction, and a comparison of renal denervation methods for resistant BP.

Aldosterone antagonists (spironolactone ... New York Heart Association functional class IV symptoms, preserved renal function and a normal potassium concentration. Spironolactone was investigated ...

Aldosterone tells the kidney and other organs to retain sodium, which helps maintain the existing fluid in the body. However, when aldosterone is inappropriately high, a condition called primary ...

Elevated aldosterone stimulates sodium reabsorption ... This specific protein facilitates the reabsorption of magnesium in the kidney tubules, resulting in low magnesium in the blood.

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It suppresses the renin-angiotensin-aldosterone system ... Postsympathectomy. Renal or hepatic impairment. Dialysis (esp. high-flux membrane). Gout. Asthma. SLE. Acute myopia.

Palatin Technologies, Inc. (NYSE American: PTN), a biopharmaceutical company developing first-in-class medicines based on ...