By sequencing DNA from a minimum of 100 individuals to establish SNP allele frequency, calculating LD strength in a region of interest prior to determining how many markers are needed, and ...

confirming that DASH achieves effective scoring of all SNP types. In each case, the peaks for the pairs of homozygous samples differ by between 5 and 9°C, enabling unambiguous allele scoring.

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types. The study was led by Ph.D.

Synopsis: In a case with implications for the litigious molecular diagnostics space and written description law, Chief Judge Connolly ...

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

“The people who have the minor allele variant of the SNP convert ethanol to acetaldehyde very rapidly. And that causes a lot of negative effects.” She went on to say that the resulting nausea ...

This practical is based on using the software package GCTA to estimate the heritability of a trait for which causal SNP effects depend on allele frequency and linkage disequilibrium patterns (Lecture ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human ...