2025年2月18日,中国科学院上海药物研究所李佳、蒋昊文及同济大学汤二将共同通讯在Nature communications上在线发表题为“Macrophage SUCLA2 coupled glutaminolysis manipulates ...
AMP-activated protein kinase (AMPK), as a key regulator of cellular energy metabolism, influences multiple pathological processes associated with MASLD. This review systematically summarizes the ...
前言既往研究证实钠-葡萄糖协同转运蛋白2抑制剂(SGLT2i)对成人慢性肾脏病(CKD)、2型糖尿病(T2DM)、慢性心力衰竭(HF)有良好的治疗作用。不仅如此,近期发表在柳叶刀子刊《EBioMedicine》的一项研究表明,SGLT2i还可以降低糖 ...
Amp (AMP) is a decentralized collateral token facilitating fast and secure payment transactions on the Flexa network. The goal of Amp is to make cryptocurrencies better equipped to be used as everyday ...
Diabetes affects millions worldwide, often triggering complications such as insulin resistance and fatty liver disease. To ...
However, the underlying mechanism by which paeonol inhibits ferroptosis in chondrocytes remains unclear. AMP-activated protein kinase (AMPK), an upstream regulator of antioxidative response, is ...
How the combination of HIIT with intermittent fasting or a low-calorie diet improves metabolic health among postmenopausal ...
Carling D, Clarke PR, Zammit VA, Hardie DG. Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA ...
Aerobic exercise activates a number of mechanisms determined by an increase in muscular contraction that stimulates AMP and AMPK, the mitogen-activated protein kinase (MAPK), the release of calcium ...