where diverse natural CDRs are combined into an antibody framework 11, using only CDR-encoding gene fragments originating from sequences formed and “proofread” in vivo. Such proofread peptide ...

This platform gives access to an expanded complementary determining region (CDR) diversity that allows for rapid discovery of antibodies against (i) therapeutically relevant epitopes, (ii ...

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Paratope-PLUS™ involves mutating each residue of an antibody's CDRs (Complementarity Determining Regions) to all 19 other amino acids, identifying every variant that retains or enhances function.

BI 771716, engineered using CDR-Life's proprietary technology and developed by Boehringer Ingelheim, represents a potential breakthrough in retinal therapy. Its unique antibody fragment design ...

Sino Biological delivers high-quality monoclonal antibody humanization services with a high degree of success (>90%) utilizing complementarity-determining region (CDR) grafting technology and ...

The first anti-amyloid monoclonal antibody -- and the first drug of any ... on the 18-point Clinical Dementia Rating-Sum of Boxes (CDR-SB) scale over 18 weeks. Mean baseline score was about ...

Portfolio Expansion: CDR111 CDR111, CDR-Life's newest clinical candidate ... AACR Poster Presentation Details Title: A novel T cell engager antibody for the treatment of HLA-A*01/KK-LC-1-positive ...

Additionally, it provides LucinaTech, an antibody humanization to identify framework and CDR residues; antibody affinity maturation for therapeutic and diagnostic application; antibody ...