This Perspective article examines the interplay between antibody diversification mechanisms and highlights the importance of constant regions in influencing the specificity and functionality of ...

A team has found two antibodies that can work together to neutralize the virus that causes COVID-19 in all its current known variations in a laboratory environment. More research is needed ...

Their new study, published in Science Translational Medicine, identifies powerful antibodies capable of neutralizing a wide range of norovirus strains. The finding could lead to the design of broadly ...

Their new study, published in Science Translational Medicine, identifies powerful antibodies capable of neutralizing a wide range of norovirus strains. The finding could lead to the design of ...

VDJ recombination is the process by which T ... This Perspective article examines the interplay between antibody diversification mechanisms and highlights the importance of constant regions ...

James Harrison earned the nickname “The Man With the Golden Arm” because his blood had a rare antibody that may have helped more than two million babies in Australia. By Amelia Nierenberg ...

Harrison's plasma contained the rare antibody Anti-D, also known as Rhesus D antibody, which is used to make the medication given to mothers whose blood is at risk of attacking their fetuses.

Diverse antibody repertoires spanning multiple lymphoid organs (i.e., bone marrow, spleen, lymph nodes) form the foundation of protective humoral immunity. Changes in their composition across lymphoid ...

The FACS antibody master mix (Table S3) was freshly prepared on ice while protected from ... Raw sequencing data was processed using CellRanger (version 6.0.2 or 6.1.2) to generate assembled VDJ ...

Simultaneous measurement of surface proteins and gene expression within single cells using oligo-conjugated antibodies offers high-resolution snapshots of complex cell populations. Signal from ...

Pro- and anti-inflammatory effector functions of IgG antibodies (Abs) depend on their subclass and Fc glycosylation pattern. Accumulation of non-galactosylated (agalactosylated; G0) IgG Abs in the ...