Discover how combining photodynamic therapy (PDT) with cisplatin enhances lung cancer treatment, promoting tumor cell ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality worldwide. Current treatment modalities are few or ...

Microglia, Pediatric Neurology, Autism Spectrum Disorder, Epilepsy, Neuroinflammation, Neurodevelopment Kaur, H. (2025) The Role of Microglia in Pediatric Neurological Disorders. Neuroscience and ...

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular bases of human diseases. Emphasis is placed on ...

SANTA FE, N.M. — A towering figure in cinema for decades, retired actor Gene Hackman spent his final years in seclusion with his wife, living with heart disease and Alzheimer's, authorities said ...

We have shown here that Pml function is crucial for the Fas, TNF, ceramide and IFN apoptotic pathways normally deputed to induce apoptosis upon DNA damage or neoplastic transformation. We have ...

SANTA FE, N.M. (AP) — Actor Gene Hackman died of heart disease a full week after his wife died from hantavirus in their New Mexico hillside home, likely unaware aware that she was dead ...

The authorities have given a new update on the investigation into the deaths of Gene Hackman and his wife Betsy Arakawa. The Hollywood star, 95, and his long-term partner, 65, were found dead at their ...

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier ... Resident cardiac macrophages, originating from the embryonic endothelium, play an ...