As cases of sleep disorders such as insomnia and sleep apnea increase, health experts are raising serious concerns about the ...

Around 50–90% of brain tumor patients that survive at least 6 months after radiotherapy experience some form of cognitive ...

Learn how nanoparticles cross the blood-brain barrier (BBB) and explore their potential in treating neurological disorders through targeted drug delivery.

Second, the study focused primarily on microglia, but other brain cells, such as astrocytes, also play a role in neuroinflammation and may be influenced by semaglutide. Future research should ...

They spotted many of the genes they suspected of responding to lecanemab expressed in microglia huddled around plaques. There were far more abundant in the lecanemab-treated case than in controls.

Neuroinflammation is triggered by the activation of microglia and astrocytes, which release pro-inflammatory factors that exacerbate neuronal damage. This inflammatory state also disrupts iron ...

Astrocytes are notoriously two-faced—calmly coddling neurons one minute, then ruthlessly consuming their synapses the next. Why these dramatic mood swings? Blame the EphA4 receptor, according to a ...

Tyrosine kinase 2 (TYK2), expressed in astrocytes and microglia, is involved in the activation of pathways triggered by proinflammatory cytokines, such as IL-23, IL-12 and type I interferons (IFNs), ...

Meanwhile the nature of how some cells, such as microglia, respond to gamma stimulation and how that affects pathology remains unclear, Tsai added. Even with a national Phase III clinical trial ...