GemVax&KAIL28日表示,成功完成了阿尔茨海默氏症治疗剂GV1001的全球2期临床试验患者的注射。据GemVax透露,GV1001的全球2期临床试验从2022年10月在美国注册首例患者开始,在美国和欧洲7个国家的43个机构进行了注射,最终结果计划在年内公布。此次临床试验以199名轻症及中等症阿尔茨海默病患者为对象,在50周内皮下注射0.56mg或1.12mg的GV1001,评价GV..

Unger was able to nip calcium transients in the bud by injecting a “puff” of sTREM2 into the mouse brain with a pipette; this temporarily silenced nearby neurons, and it did so in wild-type or TREM2 ...

Every year roughly 1,000 Canadians are diagnosed with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s disease). Some 4,000 Canadians are currently living with the disease. There are few ...

New research by IARPA has achieved the "impossible," providing the most detailed map of brain activity to date.

There are very few effective treatments to slow the symptoms of amyotrophic lateral sclerosis, also known as motor neurone ...

巨噬细胞亚群多样，功能复杂。其中，小胶质细胞（microglia）作为巨噬细胞家族中的特殊成员，广泛参与中枢免疫监视与炎症反应、神经发育及其退行性疾病等生理病理过程。自 1919 年被发现至今的一百多年里，小胶质细胞一直被认为是中枢神经系统（CNS ...

SHENZHEN -- Chinese scientists have, for the first time, confirmed the existence of microglia in the peripheral nervous system (PNS). This breakthrough provides novel insights into PNS development ...

In a study published in Cell on April 7, a research team led by Prof. LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence ...

“We found a higher number of activated microglia, which are the major immune cells in the brain,” says Zheng. While microglia play a vital role in maintaining brain health, their overactivation can ...

SHENZHEN, April 7 (Xinhua) -- Chinese scientists have, for the first time, confirmed the existence of microglia in the peripheral nervous system (PNS). This breakthrough provides novel insights ...