为探究阿卡西汀（ACA）对阿尔茨海默病（AD）的治疗潜力，研究人员开展了 ACA 对淀粉样 β（Aβ）肽诱导毒性模型中自噬通路和外泌体释放影响的研究。结果显示，ACA 能调节相关蛋白水平，减少 Aβ 和 Alix 蛋白量。这为 AD 治疗提供了新思路。

Usutu 病毒（USUV）严重影响鸟类和人类健康。为探究其与宿主细胞的相互作用机制，研究人员开展了关于 USUV NS4A 蛋白的研究。结果发现，USUV NS4A 诱导自噬，且被 p62/SQSTM1 靶向降解，这揭示了宿主抗病毒防御的新机制，为防控 USUV 感染提供新方向。

近日，南方科技大学生命科学学院神经生物学系副教授赵燕课题组在国际学术期刊 Autophagy 上发表了题为“ATG2A acts as a tether to regulate autophagosome-lysosome fusion in ...

Researchers at Zhejiang University found that acute stress increases natural repair mechanisms in the brain, while chronic ...

Edited by Ana Maria Cuervo, Albert Einstein College of Medicine, Bronx, NY; received June 7, 2024; accepted February 26, 2025 ...

*仅供医学专业人士阅读参考压力是抑郁症的重要风险因素，短期适度的压力事件有利于生存和激活大脑，而长期的慢性压力暴露则会打破情绪稳态，导致抑郁症。压力对大脑的动态调节一直是该领域科学家在努力探索的，这对于开发更有效的抗抑郁治疗策略至关重要。此前的研究发 ...

COTABATO CITY — Sixteen Bangsamoro lawmakers provided hospitals and rural health units (RHUs) in the autonomous region with P62.1 million worth of financial support, ambulances and other ...

While fasting is primarily a spiritual discipline, modern scientific research highlights its remarkable health benefits, particularly through a process known as Autophagy. The term autophagy, derived ...