DelveInsight's "CARVYKTI Market Size, Forecast, and Market Insight Report" highlights the details around CARVYKTI, a ...

The firm is also shuttering its allogeneic cell therapy platform and has tasked a new CEO to lead the company through a merger.

Zenas’ lead product candidate, obexelimab, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are broadly present across B cell lineage, to inhibit the activity of ...

We discovered defective bone marrow B-lymphopoiesis with reduced B-cell output in AAV, present already before rituximab treatment. Reduced commitment into the B-cell lineage is not due to an intrinsic ...

The chimeric fusion oncogene early B-cell factor 1–platelet-derived growth ... EBF1 is a nuclear transcription factor required for normal B-lineage specification, commitment and development.

When your doctor talks to you about your B-cell lymphoma, they'll tell you what type you have. It's an important piece of info to get, because each type of this cancer acts differently and has its ...

which rearranged the original evolutionary scenario of the lineage to follow the biological process of B cell differentiation (Figure 1B). Finally, BCR-SORT was applied to various unlabeled datasets ...

Here, we measure and analyze cell cycles in deep lineage trees of human cancer cells and mouse embryonic stem cells and develop a statistical framework to infer underlying rules of inheritance. The ...

Germline precursors and intermediates of broadly neutralizing antibodies (bNAbs) are essential to the understanding of humoral response to HIV-1 infection and B-cell lineage vaccine design. Using a ...

Horns, Vollmers et al. now reveal how antibodies of every class are created in living humans. By developing a way to reconstruct the B cell proliferation process and thereby trace the lineage of ...