为探究 BRCA 突变、年龄等因素对人输卵管(FT)分子表型的影响,研究人员对 100 多例人 FT 进行多组学分析。结果表明,BRCA1/2 携带者与非携带者在分子表型上差异极小,该研究为卵巢癌高危人群肿瘤发生的预防和早期检测提供新视角。 在女性的生殖系统中,输卵管(Fallopian tube,FT)可是个 “大功臣”,它不仅负责运送卵子,还是受精和早期胚胎发育的 “秘密基地”。然而,近年来, ...
研究人员针对 BRCA 突变携带者开展卵巢癌监测研究,发现 “爆米花” 征可早期诊断,意义重大。 卵巢癌,作为女性生殖系统中极为凶险的 “杀手”,一直威胁着众多女性的生命健康。其中,高等级浆液性卵巢癌(OC)不仅是最具侵袭性的卵巢组织学类型 ...
A comparison of patients with and without BRCA gene mutations receiving prophylactic risk-reduction surgery suggest ...
Researchers identified patients with stage I-III TNBC diagnosed between 2010 and 2021 and assessed trends in NACT use, ...
Mutations in BRCA2—a gene known to repair damaged DNA and suppress tumor formation—can predict an individual's predisposition ...
Genetic and genomic testing guide breast cancer risk assessment and treatment, as discussed by Dr. Mark Robson at the Miami ...
Triple negative breast cancer accounts for 15% of cases but causes a disproportionate number of deaths. Learn about symptoms ...
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