The breast cancer susceptibility gene 1 (BRCA1) protein forms complexes with other protein components to regulate the cellular response to DNA damage. Three studies now report the identification ...

owing to dysfunction of the breast cancer type 1 susceptibility protein (BRCA1). Indeed, mutations in BRCA1 are known to predispose individuals to hereditary breast and ovarian cancers.

Breast cancer is the most commonly diagnosed cancer among women in the U.S. and is currently one of the leading causes of ...

Technically, Pol-theta is an enzyme -- a type of protein that speeds up chemical ... but some cancers -- particularly those arising from BRCA1 or BRCA2 mutations, such as certain breast and ...