The gold standard technology that scientists use to detect DNA methylation is bisulfite genomic sequencing. It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at ...

“ […] methylation entropy is measuring different properties of a locus compared to mean methylation and CHALM, and that loci ...

In their study published in the journal Science Advances, the group analyzed whole-genome bisulfite sequencing data obtained ...

Chromatin immunoprecipitation sequencing allows for genome-wide profiling of protein-DNA interactions and of histone PTMs. GARP offers ChIP-seq library construction starting with ChIP and Input DNA.

A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 12, 2025, titled "DNA methylation entropy is a biomarker for aging." ...

Sequence context is an important control because bisulfite-treated, PCR-amplified DNA is A-T-rich, which decreases sequence variation. Pyro Q-CpG therefore guarantees that the correct sequence was ...