Once cleaved, ROCK-I is constitutively active and is responsible for bleb formation in apoptotic ... it is thought that caspases turn off cell survival and turn on cell disassembly.

In 2007, Ho Man “Holly” Tang took a break from her undergraduate biology studies at Iowa State University to join ... attack structural proteins composing the cell’s organelles, and dismantle the ...

Various nuclear shape abnormalities such as micronuclei and nuclear blebs both close to the main nucleus. Nuclear shape abnormalities can lead to a severe impact on genomic DNA integrity.