A variety of antidotes have been reported to treat SSRI-induced sexual dysfunction ... Medications enhancing dopaminergic tone include amantadine, bupropion, and stimulants, with yohimbine showing ...

Bupropion, on the other hand, is one of the few antidepressants that don’t cause these common side effects, and some research ...

Sexual dysfunction is a frequent adverse effect with all SSRIs (to a lesser extent with fluoxamine and fluoxetine compared to others), but this is less of a problem with mirtazapine and bupropion.

The mechanism of action of bupropion is unknown, as is the case with other antidepressants. However, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.