It is associated with the transmission of numerous intracellular stress signals and the subsequent regulation of gene expression. For instance, key signaling pathways such as MAPK, JAK/STAT, Notch, ...

Mechanistically, Indirubin inhibited LPS-induced activation of the EGFR/SRC/PI3K and NF-κB/MAPK pathways in macrophages, significantly reducing cell death and inflammation in RAW264.7 cells.

The phosphatidylinositol-3-kinase (PI3K) pathway plays a crucial role in cell growth and survival and is activated in various cancers. Multiple components of the pathway are frequently targeted by ...

Hong Kong Special Administrative Region of the People’s Republic of China United Kingdom to a British National (Overseas) as a person born, naturalized or registered in Hong Kong be physically present ...

Pathways Undergraduate Researchers is a competitive, full-time, paid summer internship program for rising first-, second-, and third-year college students. The program is specifically designed for ...

The authors proposed that the effect of Erk pathway would be mediated mTOR2-SGK1. The mitochondrial metabolisms appears to be involved in this regulation. This study is well performed, and the ...

During your time with Pathways to Medicine, you will participate in events and activities throughout Year 12 and 13. Every aspect of the programme is designed to help you make a strong and informed ...

Injury-induced (Wallerian) axonal degeneration is regulated via the opposing actions of pro-degenerative factors such as SARM1 and a MAPK signal and pro-survival factors, the most important of which ...