(H) SBP and UACR of pregnant mice injected with PBS, Sham mouse-derived or RUPP mouse-derived CD4 + CD44 + T cells. Data were compared between groups using one-way ANOVA and represented as mean±SEM ...

免疫浸润和富集分析：研究发现 CD44 high 组中 M2 巨噬细胞、单核细胞和 CD4 记忆静止 T 细胞的浸润较高。GO 和 KEGG 分析显示，CD44 相关的生物功能和通路包括突触组织、粘着斑、溶酶体、Epstein-Barr 病毒感染等。 影像组学模型的构建和评估：通过对 82 例患者的影像 ...

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity.

为解决急性肾损伤（AKI）机制不明及治疗策略缺乏的问题，南方医科大学研究人员探究 CD44 在 AKI 中的作用。结果发现 CD44 可加重 AKI，抑制它或成治疗新策略。推荐科研读者阅读，以了解 AKI 新机制与潜在疗法。 在当今社会，急性肾损伤（AKI）就像一个隐藏在 ...

细胞增殖的周期性是生物的一个基础特征。同样适应性免疫的抗原特异性T和B细胞通过克隆扩增产生大量短寿命的效应细胞和一些长寿命的记忆细胞。T细胞主要有两个亚群：辅助性CD4T细胞和细胞毒性CD8T细胞；随着时间推移，记忆性CD4+T和CD8+T通过细胞死亡、存活 ...

BMP4 (PeproTech) was administrated in 25 ng/µL for footpad injection in 10 µL. BMP4 neutralizing antibody (R&D system) was used in 10mg/kg for i.p. Naïve mouse (CD4+CD62L+CD44−) T cells were purified ...

Immunophenotyping of T cell populations included the identification of naïve (CD3+CD44–CD62L+), memory (CD3+CD44+CD62L+), and effector (CD3+CD44+CD62L−) T cells [CD4+ and CD8+ naïve T cells ...