分选前后的细胞用 FITC anti-mouse CD4、PE anti-mouse CD44 和 APC anti-mouse CD62L 标记后进行流式分析,分选前后的 Naive CD4+ T 细胞 纯度分别为 18.1%和 96.21%。 平台声明:该文观点仅代表作者本人,搜狐号系信息发布平台,搜狐仅提供信息存储空间服务。
CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...
为探究靶向 H 3 K27me 3 治疗神经炎症的效果,浙江大学研究人员开展了关于 EED 抑制剂对实验性自身免疫性脑脊髓炎(EAE)影响的研究。结果显示,EED 抑制剂可抑制树突状细胞(DC)迁移、缓解炎症,为自身免疫性疾病治疗提供新方向。相关成果发表在 ...
研究结果部分: "CHD8 deficiency causes effector T cell-mediated inflammatory disorders"显示,Treg特异性敲除CHD8导致小鼠出现皮肤溃疡和肺部炎症等致命性表型,流式分析证实CD4 + CD44 + 和CD8 + CD44 + 效应T细胞比例显著增加。 "CHD8 deficiency does not affect ...
The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...
There are at least 70 documented autoimmune diseases [36] and the prevalence of autoimmune disease is rapidly rising worldwide, for reasons not completely understood. [37] Although the disorders ...
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