在免疫系统中，免疫耐受的失衡是过敏性哮喘的关键致病因素。不同类型的细胞参与维持免疫耐受，其中 CD4? CD44?记忆 T 细胞与免疫耐受关系密切，而组织驻留记忆 T（TRM）细胞又是 CD4? CD44?记忆 T 细胞的重要亚型。不过，TRM 细胞在哮喘免疫耐受中的作用以及其受 ...

分选前后的细胞用 FITC anti-mouse CD4、PE anti-mouse CD44 和 APC anti-mouse CD62L 标记后进行流式分析，分选前后的 Naive CD4+ T 细胞 纯度分别为 18.1%和 96.21%。 平台声明：该文观点仅代表作者本人，搜狐号系信息发布平台，搜狐仅提供信息存储空间服务。

H3K4me3 is required for FOXP3-dependent gene activation in T reg cells. (A) Venn diagram showing overlap of H3K4me3 enriched regions (this study) and FOXP3 binding ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Syndecans (SDCs) are ...

There are at least 70 documented autoimmune diseases [36] and the prevalence of autoimmune disease is rapidly rising worldwide, for reasons not completely understood. [37] Although the disorders ...

点击蓝字关注我们【导读】癌症治疗的临床方法面临着几个相互关联的挑战，包括药物输送效率低、潜在的不良副作用和不便。2025年3月18日，四川大学/华西医院的研究团队在期刊《Nature Communications》上发表了题为“Wearable ...

Methods: To study accessibility and reproducibility in cardiovascular research reporting, we screened 639 randomly selected articles published in 2019 in three top cardiovascular science publications: ...

Institute of Medical Microbiology and Hygiene and Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University, Mainz 55131, Germany Institute of Infection ...