The cell-surface glycoprotein CD44 is involved in a multitude of important physiological functions including cell proliferation, adhesion, migration, hematopoiesis, and lymphocyte activation. The ...

By Babul Anunay, Ateet Mishra, Ashish Goel (Freescale Semiconductors Pvt. Ltd) With the increasing complexity of design in today’s fast changing world, the thrust on power saving has increased ...

To bridge the gap between theory and practice, we propose FlexTAS, a flexible and practical solution for TSN. The key insight behind FlexTAS is that relaxing gating does not introduce uncertainty, as ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In response to infections, naive CD8 T cells ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Subcutaneous LCMV infection induces T H 1 cell ...

这种治疗方法上调了CD8和CD4 T细胞中的Tem（CD44 CD62L+-），下调了Tcm（CD44 CD62L）。这些发现表明，Anti-PD1联合wf-UMP不仅能诱导特异性长期保护，还能 ...

与其他组相比，Anti-PD1+wf-UMP治疗可引起持续的抗肿瘤反应，其特点是从Tcm表型向Tem表型的显著过渡。这种治疗方法上调了CD8和CD4 T细胞中的Tem（CD44 CD62L+-），下调了Tcm（CD44 CD62L）。这些发现表明，Anti-PD1联合wf-UMP不仅能诱导特异性长期保护，还能有效预防肿瘤复发。

Flow cytometric analysis was performed by gating on MHC II/CD11c-positive populations to quantify CD80 and ... BD), CD8 (clone 53–6.7; Biolegend), CD62L (clone MEL-14; Biolegend), or CD44 (clone 1M7; ...

Constitutive activation of STING by gain-of-function mutations triggers manifestation of the systemic autoinflammatory disease STING-associated vasculopathy with onset in infancy (SAVI). In order to ...

School of Biomolecular and Biomedical Sciences and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland ...