King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide. It offers Pradefovir, Posaconazole, Voriconazole, CAPVAXIVE, NOXAFIL ...

胰腺导管腺癌(PDAC)缺乏特异性诊断标志物，尤其对CA19-9阴性患者存在检测盲区。南京鼓楼医院团队通过多组学分析发现CD44在CA19-9阴性PDAC中高表达，开发了放射性标记抗体89Zr-1M2E3实现精准影像诊断，为这类高恶性度肿瘤提供了新型诊疗靶点。 胰腺癌被称为"癌中 ...

Gastric cancer ranks among the top 5 cancer types in terms of both incidence and mortality, with a 5-year overall survival rate of only 29%. CD44 variant 6 (CD44v6) is an isoform of CD44 and is ...

多发性骨髓瘤（MM）恶性程度高、生存率低，其预后标志物的研究意义重大。研究人员针对 FRGs 在 MM 中的作用开展研究，筛选出 17 个关键基因，其中 CAV1、CD44 和 TFRC 与 MM 预后相关，有望成为预后标志物和治疗靶点，改善患者预后。 多发性骨髓瘤（Multiple Myeloma ...

Missing Protein Keeps Mice Slim, Even on a High-Fat Diet Feb. 26, 2025 — Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice ...

铁死亡肿瘤细胞通过分泌 Galectin-13 与邻近肿瘤细胞膜上的 CD44 结合来抑制 SLC7A11 的质膜定位，增强邻近肿瘤细胞铁死亡敏感性，从而引发铁死亡传播。