Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity.

Processes such as mitochondrial fission, fusion, mitophagy, changes in membrane potential, reactive oxygen species (ROS) accumulation, and oxidative phosphorylation (OXPHOS) are all linked to drug ...

Sarcomas are generally classified into soft tissue sarcomas, such as fibrosarcoma, and bone sarcomas such as chondrosarcoma, which are rare cancers in adults accounting for about 1% of all cancer ...

Ischemic heart disease (IHD) is a leading cause of disability and death worldwide, with immune regulation playing a crucial role in its pathogenesis. Various immune cells are involved, and as one of ...

对肿瘤浸润淋巴细胞的分析显示，联合治疗增强了 CD8 + T 细胞的激活，使其表达更多的干扰素（IFN）γ、CD44 以及转录因子 T-bet 和 EOMES ... 天冬酰胺剥夺还会促进 T 细胞的生物能量代谢，包括氧化磷酸化（OXPHOS）和糖酵解，同时增加谷氨酰胺和谷氨酸水平 ...