沉默KLF2促使CD8 T细胞沿着不同的分化路径发展，引导它们远离杀伤性T细胞，进入一种称为衰竭的功能失调状态，这种状态会降低这些细胞对抗感染和 ...

When they find one, they begin to multiply and send signals to other cell types to do the same. The lymphatic system forms a network similar to the blood vessels. It carries a substance called ...

The Department of Cell and Molecular Biology at Karolinska Institutet is a nationally leading academic research center of high international standard where science comes first and foremost. CMB ...

The authors analyze T cell receptor sequences from mice as they progress through positive selection, CD4/CD8 lineage commitment, and negative selection. Thereby they find small but consistent ...

In this review, we will focus on recent progresses in our understanding of two DGK isoforms, α and ζ, in CD8 T effector and memory cell differentiation, regulatory T cell development and function, and ...