The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

这些炎症因子通过旁分泌作用影响 HFF，降低线粒体膜电位，增加线粒体 ROS 水平，下调 TGF-β 1-Smad2/3 信号通路，增加 β-Gal 活性，减少 COL1A1 和 COL3A1 表达，促使 HFF 老化。而刺梨提取物可通过下调角质形成细胞的 IL-17 通路，抑制炎症反应，减轻对 HFF 的旁分泌 ...

为探究 HRAS G12S 和 G12V 突变对小鼠 MC3T3-E1 前成骨细胞分化的影响，德国乌尔姆大学研究人员开展研究。结果表明，两种突变均抑制成骨细胞分化，替匹法尼可部分挽救，这为相关骨骼疾病治疗提供新思路。 在人体中，骨骼就像一座不断翻新的 “大楼”，骨重塑 ...

We aren’t quite sure which Locus could make it into the game. Images via Marvel Comics. Remixed by Dot Esports. Interestingly, Locus is the name of two different characters who have appeared in ...

The fuse stack provides a general architecture for performing sensor fusion live on a robot. Some possible applications include state estimation, localization, mapping, and calibration.

Non-coding RNA is still one of the most popular fields in biology research. In recent years, people paid more attention to the roles of H19 in lung diseases, which expressed abnormally in various ...

Bone is a rigid connective tissue composed mainly of organic components (90% type I collagen, the rest other non-collagenous structural proteins and cells) and inorganic minerals (mostly calcium ...

The DNA inside every cell in a human body is the same, and yet the activities that occur within different types of cells can vary greatly. White blood cells, for example, are different from skin cells ...