CRISPR-Cas systems have been exploited for targeted genome editing. CRISPR-Cas12a is a programmable endonuclease used for genetic engineering. Here, the authors use real-time single-molecule ...
目前,还没有针对 DENV 的有效疫苗和特效治疗药物,因此早期检测就显得尤为重要。然而,传统的检测方法,如病毒分离、血清学检测、酶联免疫吸附试验、逆转录聚合酶链反应(RT-PCR)和实时定量 RT-PCR(qRT-PCR)等,存在着诸多不足。这些方法要么依赖特定的 DENV 抗体、昂贵的设备,要么需要专业技术人员操作,在资源有限的地区难以推广使用。
Expanding CRISPR's Potential Since its discovery, CRISPR (“Clustered Regularly Interspaced Short Palindromic Repeats”), which ...
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AZoLifeSciences on MSNA Next-Gen CRISPR Tool Just DroppedOver the past 15 years, developments in the gene-editing technique known as CRISPR-Cas9 have produced significant new ...
在CRISPR技术问世十周年之际,基因编辑领域再次迎来里程碑式突破。2025年3月《自然·生物医学工程》刊发的Cas12a基因敲入小鼠研究,不仅刷新了多重基因组工程的技术上限,更揭示了基因治疗从实验室走向临床的关键路径。数据显示,全球基因治疗市场规模预计2028年将突破500亿美元,但现有技术仍面临多重基因调控效率低(平均仅32%)、原代细胞编辑困难(成功率不足15%)等核心痛点。耶鲁大学团队此次 ...
点击蓝字关注我们【导读】人类疾病的多效应和基因相互作用网络的复杂性要求基因敲入小鼠能够进行多重基因扰乱。2025年3月20日,耶鲁大学/约翰霍普金斯医院的研究团队在期刊《Nature Biomedical ...
Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...
Cas12a tool to enable simultaneous genetic modifications, allowing the study of complex genetic interactions in immune system ...
The new tool, which is called CRISPR-Cas12a, can help researchers simultaneously assess the impact of multiple genetic changes involved in variety of immune system responses, the researchers say. "We ...
Erick J. Lucera to Step Down as CFO to pursue another opportunitySenior Vice President of Finance Amy Parison Appointed CFOCAMBRIDGE, Mass., ...
Erick J. Lucera to Step Down as CFO to pursue another opportunity Senior Vice President of Finance Amy Parison Appointed CFO CAMBRIDGE, Mass., March 20, 2025 (GLOBE NEWSWIRE) -- Editas Medicine, Inc.
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