Gut Microbiota in Immuno-Oncology: A Practical Guide for Medical Oncologists With a Focus on Antibiotics Stewardship Bispecific antibodies (bsAbs) have emerged as a novel class of therapeutics, ...

Abatacept was not associated with an increased risk for malignancy in patients with rheumatoid arthritis or psoriatic arthritis based on clinical trial data, though observational data differed. Study ...

These drugs are given as an intravenous (IV) infusion, typically every 2, 3, 4, or 6 weeks. Ipilimumab (Yervoy) and tremelimumab (Imjudo) are immune checkpoint inhibitors with a different target. They ...

Examples include therapies based on monoclonal antibodies, where γδ T cells cooperate with antibodies such as rituximab to strengthen the ADCC response; combinations with TLR modulators that influence ...

为探究植物系统生产生物仿制药的潜力，研究人员开展表达抗人 CTLA-4 抗体伊匹木单抗（Ipilimumab）的研究。结果显示，纯化的 mAb P CTLA-4 能有效识别 CTLA-4，这表明植物表达系统在生产高价值药用生物仿制药方面潜力巨大。 在癌症治疗领域，免疫疗法近年来备受 ...

After underperforming the overall market for the past few years, large-cap pharmaceutical stocks may now be positioned to outperform as the impact of tariffs on foreign products and services ...

4月3日，百济神州宣布停止TIGIT抗体Ociperlimab作为肺癌潜在治疗方法的临床开发计划。根据预先计划的无效性分析结果，独立数据监查委员会（IDMC ...

In humans, it takes 4–7 days for the adaptive immune system to mount a significant response, and in mice it may work faster, but it generally takes effect after the innate immune response. More ...

hThe Dr Henry D Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA iDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, ...