This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Hypertrophic Scar (HS) is a common fibrotic disease of the skin, usually caused by injury to the deep dermis due to trauma, burns, or surgical injury. The main feature of HS is the thickening and ...

Tammy Tam is the South China Morning Post's Editor-in-Chief and is responsible for the overall editorial direction, strategic development and leading the Post's newsroom operations for both its ...

However, increasing evidence suggests that the polarization state of macrophages is far more complex than the simplistic M1/M2 dichotomy. The IFN-TAM is a subtype that tends to exhibit ...

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States Alnylam ...

TAM 受体家族在肿瘤免疫领域愈发受到关注 ... 在胶质母细胞瘤中，阻断 MERTK 能够减少 CD206 + M2 样巨噬细胞的数量，联合放疗可显著减缓肿瘤生长，并增强 M1 样巨噬细胞的激活，从而改善炎症免疫反应。 TYRO3 受体的高表达与多种癌症相关，包括鳞状细胞癌 ...