Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity.

Speaking to TUKO.co.ke, a representative of the school, said that the school has invested heavily in resources necessary to provide top-notch training to students. Additionally, the school has ...

Police are to get new powers to enter properties without a warrant if tracking apps such as ‘Find My Phone’ show stolen gadgets are inside. Home Secretary Yvette Cooper said the move was aimed ...

We thank Professor John L. Rubenstein for his comments, suggestions, and edits. We are grateful to Professor Hua Han for sharing the Rbpj floxed mice, and Professor Jean M. Hebert for sharing ...

Naseem Shah might be the biggest threat, but he too hasn't bowled enough wicket-taking deliveries in ODIs. Expect India to notch up a routine win in this high-octane clash.

为解决急性肾损伤（AKI）机制不明及治疗策略缺乏的问题，南方医科大学研究人员探究 CD44 在 AKI 中的作用。结果发现 CD44 可加重 AKI，抑制它或成治疗新策略。推荐科研读者阅读，以了解 AKI 新机制与潜在疗法。 在当今社会，急性肾损伤（AKI）就像一个隐藏在 ...

这类细胞表面高表达CD44受体，具有三大“超能力”： 指标PL处理前PL处理后下降 ... 预防适应性耐药：长期单药使用可能激活Notch通路（检测到Jagged1表达↑2.8倍） 行业突破：采用PL+PD-1抑制剂+表观遗传药物三联方案，在临床前模型中实现CSCs清除率98%，且6个月无 ...

Human mutations in Notch signalling components have been implicated in several forms of congenital cardiovascular disease, including cardiac outflow tract defects (jagged 1, notch 2), aortic valve ...

Liver was perfused through the vena cava with 10 ml ice-cold PBS. During perfusion, the hepatic portal vein was cut to allow outflow of the blood from the liver. Afterwards, liver was gently meshed ...

Glioma is one of the most common malignant tumors of the central nervous system and is characterized by extensive infiltrative growth, neovascularization, and resistance to various combined therapies.

The biological properties of pancreatic cancer stem cells (PCSCs) remain incompletely defined and the central regulators are unknown. By bioinformatic analysis of a human PCSC-enriched gene signature, ...