(A) In a cell, motility is initiated by an actin-dependent protrusion of the cell’s leading edge, which is composed of armlike structures called lamellipodia and filopodia. These protrusive ...

Microscopic examination mostly relies on image interpretation, where the human eye analyzes cell shape, roundness, and pigmentation. Moreover, fluorescent antibodies, dyes, and tagged biomarkers can ...

WASP and N-WASP are involved in cell-shape changes that occur inwardly (endocytosis) and outwardly (filopodia and podosomes). WAVE proteins are involved in outward (lamellipodia) cell-shape ...