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生物通
7 天
芹菜籽源重组脂质纳米颗粒:缺血性脑卒中治疗的神经元靶向纳米药物
缺血性脑卒中(IS)是全球死亡的主要原因,开发有效神经保护剂面临挑战。研究人员开展芹菜籽源重组脂质纳米颗粒(CS-rLNPs)用于 IS 治疗的研究。结果发现 CS-rLNPs 可穿透血脑屏障(BBB)、靶向神经元,通过 TLR4/MyD88/NF-κB p65 通路发挥治疗作用,为 IS 治疗提供新策略。
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