为探究 STX12 缺乏的病理生理改变及致死机制，研究人员构建 Stx12 基因敲除小鼠和敲低斑马鱼模型开展研究。结果发现 STX12 缺失导致线粒体损伤、mtDNA 释放，激活 cGAS-STING 通路和炎症反应，这为揭示相关疾病机制提供了新视角。

Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan 430060, P. R. China ...

A stingray sting can be very painful and can also cause symptoms like nausea and muscle cramps. In rare cases, you may have trouble breathing. However, stingray stings are generally not fatal unless ...

Rey Nambatac got TNT coach Chot Reyes’ nod to start in Game 3 of the PBA Commissioner’s Cup Finals at the PhilSports Arena last Wednesday and didn’t disappoint. It was Nambatac’s first ...

Capital gains: Both Indian residents and NRIs can use Capital Gains Account Scheme (CGAS) to save paying capital gains tax on long-term capital gains (LTCG) on sale of land, property, equities, etc.

武汉大学张先正教授和陈巍海教授开发了一种酸响应性水凝胶（ODCM@AZD），其包裹了阿霉素（DOX）、Mn 2+ 和AZD2281，能够实现化学-免疫协同治疗。

Andrew Ravens is a Newsweek reporter. He is based in Tulsa, Oklahoma. His focus is reporting on wrestling news. He has in-depth knowledge of pro wrestling and has covered the industry extensively.

(RTTNews) - MAIA Biotechnology Inc. (MAIA), on Wednesday, announced that the United States Adopted Names or USAN Council has approved "Ateganosine" as the nonproprietary name for its ...

UPDATE: A Minnesota state senator who was caught in a sting operation resigned Thursday after he was charged with soliciting a minor for prostitution. Republican Justin Eichorn, of Grand Rapids ...

A conserved molecular pathway controlled by the proteins cGAS, STING and IRF3 can detect DNA outside of these compartments, and report it to the neighboring immune cells by secondary messengers ...

Each of our cells store their genetic information in the nucleus (genomic DNA) and mitochondria (mitochondrial DNA). A conserved molecular pathway controlled by the proteins cGAS, STING and IRF3 ...