针对糖尿病创面(DBW)愈合延迟的临床难题,南京医科大学团队创新性开发了负载降钙素基因相关肽(CGRP)的明胶甲基丙烯酰(GelMA-CGRP)水凝胶。研究发现CGRP通过抑制p53信号通路促进M2巨噬细胞极化,同时增强内皮细胞功能,显著加速创面愈合。该研究为糖尿病创面 ...
Merck has announced that the antagonist of the calcitonin gene-related peptide (CGRP) receptor telcagepant has met the primary end points in two Phase III trials to treat migraine, which is ...