The administration of chemotherapeutic drugs at maximum tolerated doses (MTDs) often induces dose-limiting toxicity in rapidly dividing tissues (intestines, bone marrow, and skin), and so patients ...

One particular challenge in the treatment of cancer is therapy resistance. An international research team has now discovered a mechanism that opens up new treatment strategies for tumors in which ...

We were the first in Europe to develop chemotherapeutic agents, and we discovered, and with The Royal Marsden NHS Foundation Trust developed, the chemotherapy drugs busulfan, chlorambucil, melphalan ...

Chemotherapy uses anti cancer (cytotoxic) drugs to destroy cancer cells. The drugs circulate throughout the body in the bloodstream. This page is about chemotherapy for large bowel (colon) cancer that ...

Bioactive glasses are clinically used for repairing small bone defects however these materials have no innate chemotherapeutic properties. Furthermore, due to the high temperatures used during the ...

Chronic chemotherapy-induced peripheral neuropathy is a substantial burden among people with cancer treated with chemotherapy ...

This pioneering study, published in Nature Structural & Molecular Biology, sheds light on the complex interplay between taxanes—widely used chemotherapeutic drugs—and microtubule acetylation ...