In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited marked ...

随着生物信息学和人工智能的不断进步，越来越多的创新工具进入了科研人员的视野，推动了科学研究的快速发展。在这些工具中，AlphaFold 3无疑是近年来最为引人注目的一个。作为DeepMind团队推出的最新版本，AlphaFold ...

Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism. In plants, gene ...

Moreover, the review discusses several alternative therapies, including RNA-based treatments, aptamers, peptide-based therapies, phage therapy, and probiotics, discussing their applications, ...

Her group has developed algorithms to predict miRNA genes and miRNA targets, and has worked on the development of the CLIP method (cross-linking and immunoprecipitation) for mapping the binding sites ...