The AP3 platform is engineered to measure compound-specific effects on the entire tumor cell protein signaling network and ...

为探究缺氧肿瘤微环境中 HIF-1α 的调控机制，研究人员发现 ROS-ATM-CHK2 轴稳定 HIF-1α 促进肿瘤血管生成，为抗血管生成疗法提供理论依据。 在肿瘤的世界里，缺氧是一个极为常见且关键的 “角色”。肿瘤在生长过程中，随着体积不断增大，内部的细胞逐渐难以 ...

🚀 Welcome to the Script Hook V GitHub! 🎮 Unlock the full potential of GTA V with Script Hook V – the essential tool for running mods and custom scripts!

The World Bank’s new mission is to end extreme poverty and boost shared prosperity on a livable planet. The "Poverty, Prosperity, and Planet. Pathways Out of the Polycrisis" report evaluates progress ...

it halted progression at the S phase through the ATR/Chk1 pathway, while in HCT-116 cells, it caused arrest at the G1 phase via the ATM/Chk2 pathway. This was accompanied by downregulation of key ...

it halted progression at the S phase through the ATR/Chk1 pathway, while in HCT-116 cells, it caused arrest at the G1 phase via the ATM/Chk2 pathway. This was accompanied by downregulation of key ...

1Department of Radiation Oncology, Inselspital Bern University Hospital, Bern, Switzerland. 2Department for BioMedical Research, Radiation Oncology, University of Bern, Bern, Switzerland. 3Graduate ...

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

What is Pathway to Purdue Agriculture? Pathway to Purdue Agriculture is a partnership between the Purdue University College of Agriculture and Ivy Tech Community College-Lafayette designed to help ...

from South Africa, seeking to flee that country for reasons of safety, will be invited into the United States of America with a rapid pathway to Citizenship," Trump wrote in a social media post.