Here, the authors report that inactivation of the CHD6 chromatin remodelling enzyme sensitizes cells to PARP inhibitors via reduced abasic site repair, PARP-1 accumulation on chromatin ...

Researchers from Guangzhou Medical University and affiliated organizations presented data from a study that aimed to investigate the disease-causing mechanism of EP400, a gene that encodes the E1A ...

State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, ...

Chemotherapeutic agents are often used to treat cancer. They combat tumor growth, but also have a number of undesirable side ...

3-Day Home Show Features Free Admission & Free Parking, Offers The Latest Trends In Home Improvement, Remodeling and Design LOVELAND, CO, UNITED STATES, January 22 ...

This review focuses on intergenerational and transgenerational epigenetic inheritance in different plants, animal species and humans, presenting the up-to-date evidence and arguments for such effects ...

Bath Fitter is our top pick overall based on user reviews and the company’s bathroom remodeling offerings ... Larger and more complex projects that involve layout changes, replacing a tub ...

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These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain ...

The fifth anniversary of the 2020 Selena Gomez album Rare will have a special celebration at Complex LA from Friday, January 10 to Sunday, January 12. Starting next Friday, Complex Presents ...

Each human telomere is composed of 10-15 kb of repetitive DNA bound by a protein complex called shelterin ... At non-telomeric sites, chromatin is assembled during S-phase when chromatin remodelling ...