The gene augmentation product was a recombinant AAV8 vector expected to express AIPL1 in both rods and cones ... Electroretinograms, however, are usually not detectable in Leber congenital amaurosis, ...

Scientists have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect. Scientists at the Icahn School of Medicine at Mount Sinai and ...

Despite only being 32, identical twins Gemma and Stella have been diagnosed with the vision loss condition glaucoma Artist Stella Stevens is at her happiest when she’s creating one of her vivid ...

Researchers at the University of Toronto see a future where a single injection under the eyelid could replace months of daily eye drops to treat glaucoma, a leading cause of blindness. A team led ...

The new research showed the share of infants who died from congenital anomalies rose significantly in states with abortion bans, suggesting a disproportionate rise in the number of women who are ...

The prevalence of pregnancy in congenital heart disease (CHD) is increasing. Maternal complications of pregnancy include stroke, heart failure, and arrhythmia. Maternal lesion complexity, unrepaired ...

Introduction Primary congenital glaucoma (PCG), a type of childhood glaucoma, is primarily treated surgically to lower intraocular pressure (IOP). Failure to intervene could result in partial, or even ...

However, babies and children can be born with cataracts, or they may develop them as they age. A congenital cataract causes the same symptoms as adult cataracts—a clouding in the lens of the eye that ...

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...

Background: Gene therapy involves introducing and editing foreign genes in the body to treat and prevent genetic diseases. Adeno-associated virus (AAV) vector has become a widely used tool in gene ...

Purposes: Recent studies have suggested that loss-of-function mutations of the tunica intima endothelial receptor tyrosine kinase (TEK) are responsible for approximately 5% of primary congenital ...