A hit shows that there is “at least in principle, a molecule out there in the universe that does what I want it to,” he says. “At least it de-risks the concept.” In addition to considering ...

Research Unit of Health Sciences and Technology, Faculty of Medicine, University of Oulu, Aapistie 5 A, 90220 Oulu, Finland Biocenter Oulu, University of Oulu, Aapistie 5 A, 90220 Oulu, Finland ...

Researchers at the University of Gothenburg have identified a molecule that helps more mitochondria function properly. Mitochondrial diseases caused by POLG mutations vary in severity. In young ...

Get Instant Summarized Text (Gist) A new AI method integrates large language models (LLMs) with graph-based models to enhance molecule creation, improving efficiency and explainability. This ...

Key Laboratory of Synthetic and Nature Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi’an 710127, China ...

we have focused our efforts on solving the crystal structure of a mouse TCR in complex with an allogeneic MHC molecule. MHC alleles can differ from one another by up to 20 amino acids and most of ...

Here we report the cryo-EM structure of ligand-free, G protein-free C3aR, providing insights into its inactive conformation. In addition, we determine the structures of C3aR in complex with the ...

SAN DIEGO--(BUSINESS WIRE)--RayThera, Inc., a recently founded biotechnology company currently focused on discovering and developing small molecule therapies in immunology, announced today that it ...