MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Using cryo-electron microscopy (cryo-EM), a team of structural and molecular biologists at Memorial Sloan Kettering Cancer Center (MSK) set out to investigate G4s -- which have gained attention as ...

Six years before the start of the COVID-19 pandemic, an Ebola outbreak in West Africa had people fearing the possibility of a ...

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly ...

Thermo Fisher Scientific Inc., the world leader in serving science, has announced a Technology Alliance Agreement with the ...

Scientists at Forschungszentrum Jülich have now been able to gain fascinating new insights using cryo-electron microscopy. Their work is published in the journal Nature Structural & Molecular ...

The macromolecular organization of photosynthetic complexes within the thylakoids of higher plant chloroplasts has been a topic of significant debate. Using in situ cryo-electron tomography, this ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

The discovery, published in the peer-reviewed journal Nature, is stated to have far-reaching implications, helping us to ...

To answer this question, Dr. Qi and his colleagues used cryo-electron microscopy (cryo-EM). By freezing molecules at temperatures around minus 196 C (about minus 320 F) and bombarding them with ...

By combining advanced electron microscopy with computational reconstruction algorithms, electron tomography provides unprecedented insights into the internal structure, composition, and properties of ...