Circle Pharma, a clinical-stage biopharmaceutical company focused on developing cell-permeable macrocycle therapeutics, today announced that Chief Executive Officer David Earp, JD, Ph.D., will present ...

In this article, García-Vázquez et al. report valuable findings demonstrating that G2 and S phases expressed protein 1 (GTSE1), is a previously unappreciated non-pocket substrate of the cyclin ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

South San Francisco-based Circle Pharma is a clinical-stage biopharmaceutical company harnessing the power of macrocycles to develop therapies for cancer and other serious illnesses. The company ...

Ono Pharma and Boehringer Ingelheim both added to their cancer pipelines, licensing drugs from LigaChem Bio and Circle Pharma, respectively. Ono's deal with South Korean antibody-drug conjugate ...

State Key Laboratory of Tree Genetics and Breeding, Co-Innovation Center for Sustainable Forestry in Southern China, Jiangsu Key Laboratory for Poplar Germplasm Enhancement and Variety Improvement, ...

Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots?

机体被同一病原微生物再次感染时，免疫系统能够通过比第一次应答更快、更强的免疫反应来控制感染、减轻或阻止疾病发展。这种免疫记忆力，主要依靠能识别该病原的淋巴细胞承载。理解免疫记忆如何产生，对于开发抗感染疫苗和治疗自身免疫性疾病都具有重要的理论和实践指导 ...

Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, China Background: Early diagnosis and ...