为探究无细胞 DNA(cfDNA)中富含 GC 的 DNA(GC-DNA)对癌细胞的作用,研究人员开展了 GC-DNA 对野生型 MCF7 细胞(wt MCF7)和 TLR9-/-MCF7 细胞生存基因转录活性影响的研究。结果发现 TLR9-/-MCF7 细胞经 GC-DNA 刺激后相关信号级联活性及生存基因表达下降,该信号级联可作 ...
DNA is made up of adenine-thymine (AT) bonds and guanine-cytosine (GC) bonds. The frequency of each type of bond differs substantially across bacterial species. A new study uses this quirk of ...