Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power.

近日，深圳大学医学部基础医学院及卡尔森国际肿瘤中心朱卫国教授团队在《自然》杂志在线发表了题为 “Histone H1 deamidation facilitates chromatin relaxation for DNA repair” 的研究论文 ...

在深圳大学“2035追求卓越研究计划”和医学部“有组织科研行动计划”的大力支持下，朱卫国教授团队二十年来专注于肿瘤表观遗传调控、组 蛋白质 修饰调控 DNA ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for ...

Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for innovative therapeutic strategies.

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

这项研究首次揭示了H1去酰胺化在DNA损伤修复中的重要作用，并提出了一种全新的分子机制模型，相关研究发现不仅丰富了科学家们对染色质动态调控的理解，还为开发新的癌症治疗策略提供了理论基础。通过调节CTPS1的活性或直接靶向H1去酰胺化位点，未来研究人员 ...