在 DNA 损伤响应（DDR）机制尚未完全明晰的背景下，研究人员开展了关于组蛋白乙酰转移酶 CBP 在 DNA 损伤后通过 ATM 调节 DDR 作用的研究。结果发现 CBP 参与 ATM 激活和 DNA 双链断裂修复，这为癌症治疗中调控细胞对 DNA 损伤剂的反应提供了潜在靶点。

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

Kundu and James Clement discovered that the brain represses the acetylation of DNA-associated proteins, histones, or proteins that give chromosomes structural support in mice with a mutated syngap ...

Historically, therapies for ASD and ID have primarily targeted managing symptoms, such as behavioral issues or communication ...

A new research paper was published in Oncotarget, Volume 16, on March 21, 2025, titled “NSD2-epigenomic reprogramming and ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

Researchers at the University of Cologne have found that mRNA-based COVID-19 vaccines have a lasting impact on the innate ...

Cellular aging involves growth arrest and epigenetic alterations, offering insights into therapeutic approaches for enhancing ...

Genetic testing, also known as DNA testing, involves obtaining DNA from a sample of cells in your body to identify specific genes, chromosomes, or proteins, including those that are faulty (known as ...

A research team led by Dr. Li Yunhai from the Institute of Genetics and Developmental Biology of the Chinese Academy of ...

1Gynaecology and obstetrics, Wuxi Maternity and Child Health Care Hospital, Women’s Hospital of Jiangnan University, Jiangnan University, Wuxi, China.