Free DNA nucleotides – needed to form the new strands. DNA polymerase – an enzyme that adds new nucleotides to a growing strand of DNA. Primers – A primer is a short strand of nucleotides th ...

Scientists have yet to identify a polymerase that can add bases to ... The study of DNA replication started almost as soon as the structure of DNA was elucidated, and it continues to this day.

DNA is a complex molecule that consists of two strands coiled around each other to form a double helix structure. Comparison of a single ... for the synthesis of a new complementary strand. DNA ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the ...

The team focused on T7 DNA polymerase’s thioredoxin binding domain (TBD), which has a structure similar to that of most thermostable polymerases, including Taq. Thioredoxin, which is ubiquitous in ...

In the folded fork structure shown in the inset, the lagging-strand DNA polymerase remains tied to the leading-strand DNA polymerase. This allows the lagging-strand polymerase to remain at the ...

An RNA polymerase II molecule is about 15 nanometers across, or roughly 5,000 times smaller than the width of a human hair. This image was created by reconstructing X-ray diffraction crystallography ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

The work provides a detailed three-dimensional picture of the virus's polymerase and its key features. Understanding the structure and behavior of this critical piece of the viral machinery ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...