Researchers at the University of Cologne found that mitochondrial dysfunction leads to early skeletal aging by disrupting ...

Some of these cancerous mutations in DNA are inherited, while others arise from errors that occur as a cell divides.

Detailed price information for Zentalis Pharmaceuticals Inc (ZNTL-Q) from The Globe and Mail including charting and trades.

Proteins are fundamental biomolecules that perform a broad range of vital functions within the human body. They serve as an essential structural and functional component of cells, tissues and organs ...

Human life starts as a single cell that divides numerous times to create an entire human body consisting of trillions of cells. To maintain genome stability, cells need to faithfully replicate their ...

Replication stress ... such as those that mediate DNA repair and cell-cycle checkpoints, can also contribute to an unstable genome. A gene that encodes an RNA or protein that can directly or ...

The presented evidence is conclusive for the involvement of m6A in DNA involving single cell imaging and mass spectrometry data. The authors present convincing evidence that the m6A signal does not ...

We show that saccharin mediates its antimicrobial activity via bulge-mediated cell lysis rather than through impacting DNA replication dynamics. We reveal that saccharin can inhibit a range of ...

通过构建计算细胞周期模型，发现不同类型 SVs 在 DNA 修复和复制过程中产生，为研究 CIN 和肿瘤进化提供新视角，具有重要意义。 在癌症研究的舞台上，染色体不稳定性（Chromosomal instability，CIN）如同一个神秘的 “幕后黑手”，广泛存在于人类肿瘤中，它常常 ...

This phosphorylation allows recruitment to the gapped DNA structure found in single-strand DNA (ssDNA) nicks and/or gaps between Okazaki fragments (OFs) during DNA replication. T118A ...