Two new studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a ...

Researchers have uncovered mechanisms by which mobile genetic elements integrate into the chromosomes of bacteria with linear genomes.

Linker DNA, upwards of 80 base pairs ... revealed and gradual emergence of chromatin structure recapitulated by polymer simulations. Eukaryotic chromosomes are organized into arrays of compact ...

Analysis of Circular DNA Source Region and Related Coding Genes To analyze eccDNAs/ecDNAs distribution in the whole-genome chromosome region, we split each chromosome into 50kb windows, counted the ...

Figure 2. G4s contribute to cellular senescence. G4 structures contribute to nearly all of the senescence pathways in the cell, such as DNA damage, telomere shortening, chromatin structure, stress ...

Scientists found that fast-evolving DNA shaped human brain development but might also increase risks for mental disorders.

In the absence of DDM1 and RNAi, this TE doesn’t produce small RNAs, so the centromere is not methylated. These mutants also ...

Genetic screening can be a game-changer for women’s health, enabling proactive steps in preventing and managing diseases like ...

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.