Cryo-EM structures reveal that DSR2, a defense-associated sirtuin, recognizes SPR phage tail tube protein, activating its NADase activity and elucidating its role in bacterial anti-phage immunity ...

Figure 1 Location of the cold seep sites surveyed at Formosa ridge. Topographic map shows the tectonic features. The study area is delimited by the red dot. Because the understanding of biomass, ...

为探究细菌防御相关沉默调节蛋白（DSR）系统激活机制，中国医学科学院等机构研究人员开展研究，揭示了枯草芽孢杆菌 DSR2 系统激活机制，为理解细菌抗噬菌体防御提供依据。 在微观的微生物世界里，细菌与噬菌体之间时刻上演着激烈的 “战争”。噬菌体 ...

The Arctic and Subarctic seas are predicted to become hotspots for marine heatwaves (MHWs). High-latitude marine ecosystems face unique consequences from accelerated warming and sea ice loss, ...

Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of ...

The P4 ATPases use ATP hydrolysis to transport large lipid substrates across lipid bilayers. The structures of the endosome- and Golgi-localized phosphatidylserine flippases—such as the yeast Drs2 and ...