Diastolic heart failure is defined clinically when signs and symptoms of heart failure are present in the presence of preserved left ventricular systolic function (ejection fraction >45%).

Changes in the heart might mean more than just cardiovascular risk – they could also signal early shifts in brain health. A ...

A new study uncovers compelling evidence that even subtle heart issues may affect brain structure — potentially years before ...

The meta-analysis found that heart dysfunction, especially diastolic problems, could be associated with reduced brain volume ...

The objectives and the potential therapeutic approaches for primary diastolic heart failure are outlined in Table 7. Most patients present with symptoms related to pulmonary and systemic venous ...

People who have early signs of heart problems may also have changes in brain health that can be early signs of dementia, such ...

"Evaluating people who have heart problems—especially impaired diastolic function—for problems with memory and thinking skills could help us detect any cognitive decline early and start ...

Based on the Phase II data, Imbria Pharmaceuticals’ inerafaxstat could complement existing treatments rather than replace ...

A gene therapy for heart failure with preserved ejection fraction (HFpEF), also known as diastolic heart failure, has shown ...

“Impulse Dynamics has established leadership and commitment to significantly changing the treatment options available for HF patients,” said Jason Spees, CEO of Impulse Dynamics. “The expanded ...

Tenaya Therapeutics (TNYA) announced the publications of positive preclinical data for TN-201, the company’s gene therapy candidate for ...

CCM therapy is now indicated for symptomatic heart failure patients with diastolic or systolic ventricular dysfunction, offering a broader range of patients a new option for improving quality of life ...