1Institute of Cellular and System Medicine, National Health Research Institutes, Miaoli, Taiwan. 2Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan.

In a Phase IIa trial, CAN-2409 (also known as aglatimagene besadenovec) demonstrated median overall survival (OS) of 24.5 months in patients who had failed checkpoint inhibitor therapy — more than ...

CAN-2409 extended median overall survival to 24.5 months in NSCLC patients, surpassing standard docetaxel chemotherapy outcomes. The treatment showed a significant survival benefit in non-squamous ...

Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China ...

In this Research Topic, Zhu et al. summarised and discussed recent advances in 3D modeling for liver cancer research, including the creation of 3D models, traditional 3D cell culture techniques, and ...

One important complication of vasopressors to be aware of is extravasation. When the drug leaks out of the vein into the interstitial space, the alpha effects of the vasopressors can constrict ...

The multi-step extravasation cascade in vivo is described, followed by an in-depth guide on how to model this process on a chip. Next to chip design, creation of a chemotactic gradient and ...