A new study shows that dysfunction of lysosomes can cause leakage of toxic substances within brain cells, contributing to ...

Researchers from Aarhus University and Synuca Therapeutics recently presented a novel drug-like small-molecule inhibitor of sarco/endoplasmic reticulum calcium ATPase (SERCA), SYN-4569, with superior ...

Day 32 of NEET 45-Day Challenge focuses on top repeated questions in Physics, Chemistry, and Biology, covering key topics ...

在肿瘤细胞的 “生存游戏” 里，铜元素扮演着十分关键的角色，适量的铜能助力肿瘤生长，可过量的铜却会引发一种名为铜死亡（cuproptosis）的细胞程序性死亡。这本是对抗肿瘤的有力 “武器”，然而，铜死亡在 LUAD 中究竟有着怎样的作用，长期以来却如同迷雾，让科研人员难以看清。为了揭开这层神秘面纱，来自江苏省人民医院和南京医科大学第一附属医院等机构的研究人员踏上了探索之旅。

为探究糖尿病脑病（DE）发病机制及治疗靶点，研究人员开展了关于磷脂酸磷酸酶 Lipin1 对 DE 影响的研究。结果发现 Lipin1 可改善 DE 小鼠病理变化，或成为治疗 DE 的新潜在靶点，为 DE 治疗提供了新方向。

Researchers used integrated Mendelian randomization in a cohort of over 247,000 individuals to identify 62 plasma proteins associated with breast cancer risk. Nine high-confidence targets, including ...

Scientists apply principles of math and physics to unravel the mystery of how the endoplasmic reticulum, an organelle vital ...

A natural compound found in common fruits and vegetables may help treat neurodegenerative diseases, according to new research ...

Mesencephalic astrocyte-derived neurotrophic factor (MANF), a novel endoplasmic reticulum stress-induced neurotrophic factor, exerts a protective role in both nervous and non-nervous systems. However, ...

A recent study from the University of Missouri suggests that a compound found in certain fruits and vegetables may hold the key to treating neurodegenerative diseases. A natural compound commonly foun ...

A natural substance found in everyday fruits and vegetables might one day help treat serious brain and nerve diseases like ...